This book covers most of the topics with latest information on bone in general and research on bone healing in particular. The book is divided into 27 chapters covering almost all aspect of orthopaedic research in small and lab animals including basic knowledge about bone; fracture types and fracture healing; bone grafts and bone substitute; internal fracture fixation; external fracture fixation; bone morphogenetic protein; transforming growth factors; role of mesenchymal stem cell in osteoinduction; fracture healing in critical sized bone defect and in very large bone defect, effect of herb and herbal product in fracture healing, role of different hormones, anabolic steroid, NSAID drug, bone wax, ultrasound in fracture healing; minimal invasive fracture repair; management of comminuted femoral and tibial metaphyseal fracture; endocrine role of fracture healing; evaluation of bone graft, ceramic biomaterials in fracture healing and physiotherapy of orthopedic patients.
This book includes different research findings on application of herb, herbal product, bone graft, ceramic biomaterials, mesenchymal stem cells, and different osteoinducers in bone regeneration.
The main objective of this book is to provide the latest information to meet the requirements of not only undergraduate and post graduates research scholars but also to the teachers, biologists and clinician involved in animal treatment and orthopaedic research.
The book contains more than 150 good quality photographs of internal fixation techniques, x-ray, undecalcified ground sections, scanning electron microscopy, 3-D CT scan, histopathogical stained sections used in different orthopaedic interventions.
This book would be of immense use to the students, teachers and research scholars engaged in the field of orthopaedic research.
1. Bone-Basic Consideration, 2. Fracture Types and Fracture Healing, 3. Role of Different Minerals Vitamins and Hormones in Fracture Healing in Animals, 4. Bone Grafts, Bone Substitutes and Bone Bioimplants in Small Animals Orthopaedics, 5. Internal Fracture Fixation in Small Animal, 6. Application of Plaster Cast/Splint for Fracture Immobilization and Other Bandaging Procedure in Small Animals, 7. Bone Morphogenetic Proteins-Novel Regulators of Bone Formation, 8.Transforming Growth Factor Beta (TGF-?) in Bone Remodeling, 9. In vitro Osteoinduction Potential of Silica Coated Hydroxyapatite Bioscaffold Seeded with Mesenchymal Stem Cell, 10. Mesenchymal Stem Cells of Different Origin in Regeneration of Critical Sized Bone Defect, 11. Mesenchymal Stem Cells Seeded Bioceramic Construct for Bone Regeneration in Large Critical-Size Bone Defect, 12. Embryonic Stem Cell (ESC) Hydroxyapatite Construct with Growth Proteins for the Repair of Bone Defects, 13. Effect of Herbal Magacal on Fracture Healing, 14. Effect of Bone Wax on Fracture Healing, 15. Effect of Prostaglandin (PGE2) on Fracture Healing, 16. Effect of Gonadotropic Hormone (Gnrh) on Fracture Healing, 17. Evaluation of Herb, Cissus Quadrangularis (Hardjore) on Fracture Healing, 18. Role of Anabolic Steriod on Fracture Healing, 19. Role of Sex Hormone Progesterone on Fracture Healing, 20. Effect of Ultrasound Therapy on Fracture Healing, 21. Effect of Non-Steroid Anti-Inflammatory Drug (NSAID) on Fracture Healing, 22. Minimally Invasive Fracture Repair Techniques and Biological Osteosynthesis, 23. Management of Comminuted Femoral Fracture by Different Internal Fixation Techniques, 24.Comparative Study of Two Different Fixation Techniques in the Management of Tibial Metaphyseal Fracture, 25. Endocrine Responses on Fracture Healing, 26.Evaluation of Composite Bone Grafts and Ceramic Implants in Fracture Healing, 27. Physiotherapy and Postoperative Rehabilitation for Orthopedic Patients